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Bone Marrow Transplant: What to Expect Before, During and After

By Dr. Varun Rajan · 17 Oct 2026

Bone Marrow Transplant: What to Expect Before, During and After

A bone marrow transplant (BMT), also called a stem-cell transplant, replaces damaged blood-forming cells with healthy ones.

What is a bone marrow transplant?

It restores healthy stem cells after disease or high-dose treatment has destroyed the marrow. Cells can come from the patient (autologous) or a matched donor (allogeneic).

What happens before?

Workup tests, matching for donor transplants, and a conditioning regimen of chemotherapy — sometimes with radiation — to prepare the body.

What happens during?

Healthy stem cells are infused through a vein, like a transfusion, then travel to the marrow and make new blood cells over weeks.

What is recovery like?

Close monitoring for infection and engraftment, often with a hospital stay, then a gradual return to normal activity over months.

Where is BMT done in Kerala?

Dr. Varun Rajan performs bone marrow transplants at Medical Trust Hospital, Kochi.

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